{"id":4440,"date":"2022-07-04T12:26:51","date_gmt":"2022-07-04T10:26:51","guid":{"rendered":"https:\/\/dev.plasmaconcept.de\/marrow-cellution\/"},"modified":"2025-11-20T14:45:50","modified_gmt":"2025-11-20T13:45:50","slug":"marrow-cellution","status":"publish","type":"page","link":"https:\/\/dev.plasmaconcept.de\/en\/marrow-cellution\/","title":{"rendered":"Marrow Cellution"},"content":{"rendered":"<section class=\"l-section wpb_row us_custom_8eed7b40 slider_unterseite height_auto width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"g-cols wpb_row arteficalslider via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default reversed stacking_default\" style=\"--gap:0px;\"><div class=\"wpb_column vc_column_container us_custom_95304ca2 leftbox has_bg_color\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column us_custom_cd781b90 hide_mobile has_text_color\"><div class=\"wpb_wrapper\"><h1 class=\"slidertypo\">Harvesting cancellous bone with just one puncture<\/h1>\n<\/div><\/div><div class=\"wpb_text_column us_custom_6df4bc3a has_text_color\"><div class=\"wpb_wrapper\"><p>The innovative MARROW CELLUTION\u2122 technology ensures controlled movement of the aspiration cannula within the marrow cavity. This allows aspiration from multiple locations within the marrow space using only a single puncture.<\/p>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container us_custom_87eb20ae rightbox has_bg_color\"><div class=\"vc_column-inner\"><div class=\"w-html\"><div class=\"desk-spacer\" style=\"height:500px;\"><\/div>\n<div class=\"mobile-spacer\" style=\"height:220px;\"><\/div><\/div><div class=\"w-html\"><div style=\"clear:both;\"><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row schmallercontentprodukte24 height_medium\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column produkt_intro_text\"><div class=\"wpb_wrapper\"><h2>SYSTEM FOR BONE MARROW ASPIRATION AND CANCELLous BONE HARVESTING<\/h2>\n<p>MARROW CELLUTION\u2122 enables optimal cell yield and meets the desire of many users for a single minimal puncture in order to keep patient burden and infection risk as low as possible. It is particularly suitable for the treatment of subchondral pathologies, bone necrosis, and\u2014when combined with Hyalofast\u00ae\u2014for the treatment of osteochondral lesions.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_a4fbd29b breiterebloecke height_auto width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_grid cols_3 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:20px;\"><div class=\"wpb_column vc_column_container highlightboxprodukt oblue\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column produktehighlightbox\"><div class=\"wpb_wrapper\"><h4>Innovation<\/h4>\n<ul>\n<li>Minimizes dilution with peripheral whole blood<\/li>\n<li>Closed system<\/li>\n<li>Controlled movement of the cannula within the cavity<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container highlightboxprodukt ogreen\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column produktehighlightbox\"><div class=\"wpb_wrapper\"><h4>Efficiency<\/h4>\n<ul>\n<li>Minimally invasive<\/li>\n<li>One puncture \u2013 multiple aspirations<\/li>\n<li>Low aspirate volume \u2013 high cell yield<\/li>\n<li>No centrifugation required<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container highlightboxprodukt oorange\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column produktehighlightbox\"><div class=\"wpb_wrapper\"><h4>Performance<\/h4>\n<ul>\n<li>Higher CFU-f count per ml<\/li>\n<li>Simultaneous harvesting of autologous bone graft<\/li>\n<li>Sterile field is not exited<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row schmallercontentprodukte24 height_medium\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"w-tabs layout_hor style_trendy switch_click\" style=\"--sections-title-size:1em\"><div class=\"w-tabs-list items_3 align_none\"><div class=\"w-tabs-list-h\"><button class=\"w-tabs-item active\" aria-controls=\"content-je1f\" aria-expanded=\"false\"><span class=\"w-tabs-item-title\">Innovative system<\/span><\/button><button class=\"w-tabs-item\" aria-controls=\"content-af46\" aria-expanded=\"false\"><span class=\"w-tabs-item-title\">The solution<\/span><\/button><button class=\"w-tabs-item\" aria-controls=\"content-y6b7\" aria-expanded=\"false\"><span class=\"w-tabs-item-title\">Maximum cell yield<\/span><\/button><\/div><\/div><div class=\"w-tabs-sections titles-align_none icon_chevron cpos_right\"><div class=\"w-tabs-section active\" id=\"je1f\"><button class=\"w-tabs-section-header active\" aria-controls=\"content-je1f\" aria-expanded=\"true\"><div class=\"w-tabs-section-title\">Innovative system<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-je1f\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>INNOVATIVE SYSTEM FOR BONE MARROW ASPIRATION AND CANCELLous BONE HARVESTING \u2013 WITH JUST ONE PUNCTURE<\/h3>\n<\/div><\/div><div class=\"g-cols wpb_row us_custom_2ae65f69 orthovisc_content_block1 via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>\u2022 MARROW CELLUTION\u2122 is an innovative instrument for harvesting bone marrow and cancellous bone<\/strong><br \/>\n<strong>\u2022 MARROW CELLUTION\u2122 enables bone marrow aspiration with a high cell concentration<\/strong><br \/>\none puncture \u2013 multiple aspiration sites within the marrow cavity<br \/>\n<strong>\u2022 The use of MARROW CELLUTION\u2122 is associated with<\/strong><br \/>\nsignificant savings in time and resources<br \/>\nreduced patient trauma<br \/>\nlower morbidity and reduced infection risk<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"af46\"><button class=\"w-tabs-section-header\" aria-controls=\"content-af46\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">The solution<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-af46\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>Solutions for every application<\/h3>\n<\/div><\/div><div class=\"g-cols wpb_row via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><div>\n<p>To meet the specific needs of users, MARROW CELLUTION\u2122 can be used both for the extraction of concentrated bone marrow aspirate and for the harvesting of autologous cancellous bone.<\/p>\n<p>The functional design of MARROW CELLUTION\u2122 is characterized by two special features that reduce the disadvantages of conventional trocar needles:<\/p>\n<\/div>\n<ul style=\"padding-top: 20px;\">\n<li>A closed aspiration cannula at the distal end prevents the suction of excess blood from the access channel<\/li>\n<li>A hand grip with a helical thread allows controlled vertical repositioning of the aspiration point within the marrow cavity<\/li>\n<\/ul>\n<\/div><\/div><div class=\"w-image us_custom_2ae65f69 align_none\"><a ref=\"magnificPopup\" href=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image1.jpeg\" aria-label=\"marrow_selution_produktseite_content_image1\" class=\"w-image-h\"><img decoding=\"async\" width=\"568\" height=\"193\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image1.jpeg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image1.jpeg 568w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image1-300x102.jpeg 300w\" sizes=\"auto, (max-width: 568px) 100vw, 568px\" \/><\/a><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p class=\"bildunterschrift\">Fig. 1: The distally closed aspiration cannula of MARROW CELLUTION\u2122<\/p>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><div class=\"wpb_text_column wpb_content_element\">\n<div class=\"wpb_wrapper\">\n<p>The functional design of MARROW CELLUTION\u2122 is characterized by two special features that reduce the disadvantages of conventional trocar needles:<\/p>\n<ol>\n<li>A closed aspiration cannula at the distal end prevents suction of excess blood from the access channel<\/li>\n<li>A hand grip with a helical thread enables controlled vertical repositioning of the aspiration point within the marrow cavity<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div><\/div><div class=\"w-image us_custom_0f8f44b7 align_center\"><a ref=\"magnificPopup\" href=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image2.jpeg\" aria-label=\"marrow_selution_produktseite_content_image2\" class=\"w-image-h\"><img decoding=\"async\" width=\"274\" height=\"209\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image2.jpeg\" class=\"attachment-large size-large\" alt=\"\" loading=\"lazy\" \/><\/a><\/div><div class=\"wpb_text_column us_custom_4127d55d\"><div class=\"wpb_wrapper\"><p class=\"bildunterschrift\">Fig. 2: MARROW CELLUTION\u2122 MC-RAN-8 for percutaneous harvesting of cancellous bone<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"y6b7\"><button class=\"w-tabs-section-header\" aria-controls=\"content-y6b7\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Maximum cell yield<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-y6b7\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>MAXIMUM CELL YIELD, EASY APPLICATION<\/h3>\n<\/div><\/div><div class=\"g-cols wpb_row us_custom_f79f129a via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container us_custom_4de32527\"><div class=\"vc_column-inner\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"324\" height=\"296\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image3.jpg\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image3.jpg 324w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image3-300x274.jpg 300w\" sizes=\"auto, (max-width: 324px) 100vw, 324px\" \/><\/div><\/div><div class=\"wpb_text_column us_custom_2ae65f69\"><div class=\"wpb_wrapper\"><p class=\"bildunterschrift\">Fig. 3: Conventional bone marrow extraction using a trocar<\/p>\n<\/div><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>The quality of bone marrow aspirate is measured by the quantity of stem and progenitor cells. Obtaining the highest possible quality aspirate often requires multiple punctures and the collection of small volumes (1\u20132 ml) from different locations.<sup>1\u20135<\/sup><br \/>\nIf the aspirated volume of 1\u20132 ml per aspiration site is exceeded, dilution with blood occurs.<sup>1\u20133<\/sup><\/p>\n<p>Trocar needles with lateral holes aspirate bone marrow primarily through the distal end of the cannula. As a result, the aspirate contains a high proportion of peripheral whole blood. To achieve the desired cell concentration, further processing (e.g., centrifugation) becomes necessary.<\/p>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"324\" height=\"296\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image4.jpg\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image4.jpg 324w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image4-300x274.jpg 300w\" sizes=\"auto, (max-width: 324px) 100vw, 324px\" \/><\/div><\/div><div class=\"wpb_text_column us_custom_2ae65f69\"><div class=\"wpb_wrapper\"><p class=\"bildunterschrift\">Fig. 4: MARROW CELLUTION\u2122<\/p>\n<\/div><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>The innovative MARROW CELLUTION\u2122 technology ensures controlled movement of the aspiration cannula within the marrow cavity. This allows aspiration from multiple locations within the marrow space using just a single puncture.<\/p>\n<p>MARROW CELLUTION\u2122 is closed at the distal end and aspirates bone marrow exclusively through holes positioned perpendicular to the insertion channel. This minimizes dilution of the aspirate with peripheral blood. MARROW CELLUTION\u2122 enables optimal cell yield and meets the desire of many users for a single puncture, keeping patient burden and infection risk as low as possible.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"g-cols wpb_row us_custom_f79f129a via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container us_custom_4de32527\"><div class=\"vc_column-inner\"><div class=\"w-image us_custom_0f8f44b7 align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"1024\" height=\"341\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image5.jpg\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image5.jpg 1024w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/marrow_selution_produktseite_content_image5-300x100.jpg 300w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/div><\/div><div class=\"wpb_text_column us_custom_b2452879\"><div class=\"wpb_wrapper\"><p class=\"bildunterschrift\">Fig. 5: MARROW CELLUTION\u2122 compared with centrifuge systems and conventional trocar needles (comparison of cell yield)<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-separator size_medium with_line width_default thick_1 style_solid color_border align_center\"><div class=\"w-separator-h\"><\/div><\/div><div class=\"wpb_text_column us_custom_15f9d3f2\"><div class=\"wpb_wrapper\"><h2>Stem cells \u2013 versatile helpers in modern medicine<\/h2>\n<\/div><\/div><div class=\"g-cols wpb_row us_custom_477ec717 via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column us_custom_2ae65f69\"><div class=\"wpb_wrapper\"><p>Stem cells are a heterogeneous group of undifferentiated cells with the ability for long-term self-renewal and plasticity. They can migrate into diseased tissues, produce and secrete bioactive molecules, and can also exert immunosuppressive effects.<\/p>\n<p>According to the German Research Foundation (DFG), stem cells have so far been identified in 20 organs of the human body. They play a key role in embryonic development and regenerative processes. Over the past decades, stem cells have become an important focus of medical research, including in the fields of reconstructive surgery and orthopedics.<\/p>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column us_custom_2ae65f69\"><div class=\"wpb_wrapper\"><p><strong>The types of stem cells currently in the focus of research are<\/strong><\/p>\n<p>\u2022 embryonic stem cells (ESC)<br \/>\n\u2022 induced pluripotent stem cells (iPSC)<br \/>\n\u2022 and mesenchymal stem cells (MSC)<\/p>\n<p>MSCs are a group of stem cells that can be obtained from bone marrow.<\/p>\n<p>These so-called BM-MSCs (bone marrow-derived MSCs) have a high regenerative potential and can stimulate healing processes in cartilage and bone.<sup>5<\/sup><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section>\n","protected":false},"excerpt":{"rendered":"Harvesting cancellous bone with just one puncture The innovative MARROW CELLUTION\u2122 technology ensures controlled movement of the aspiration cannula within the marrow cavity. This allows aspiration from multiple locations within the marrow space using only a single puncture. SYSTEM FOR BONE MARROW ASPIRATION AND CANCELLous BONE HARVESTING MARROW CELLUTION\u2122 enables optimal cell yield and meets...","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-4440","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Plasmaconcept - Marrow Cellution: Gewinnung von Spongiosa<\/title>\n<meta name=\"description\" content=\"Die innovative Technologie von MARROW CELLUTION\u2122 sichert eine kontrollierte Bewegung der Aspirationskan\u00fcle innerhalb des Markraums.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Plasmaconcept - 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