{"id":4430,"date":"2022-07-04T12:24:33","date_gmt":"2022-07-04T10:24:33","guid":{"rendered":"https:\/\/dev.plasmaconcept.de\/hyalofast\/"},"modified":"2025-11-20T14:46:02","modified_gmt":"2025-11-20T13:46:02","slug":"hyalofast","status":"publish","type":"page","link":"https:\/\/dev.plasmaconcept.de\/en\/hyalofast\/","title":{"rendered":"Hyalofast"},"content":{"rendered":"<section class=\"l-section wpb_row us_custom_3f43bdb9 slider_unterseite height_auto width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"g-cols wpb_row arteficalslider via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default reversed stacking_default\" style=\"--gap:0px;\"><div class=\"wpb_column vc_column_container us_custom_95304ca2 leftbox has_bg_color\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column us_custom_cd781b90 hide_mobile has_text_color\"><div class=\"wpb_wrapper\"><h1 class=\"slidertypo\">The Matrix for Supporting Chondrogenesis<\/h1>\n<\/div><\/div><div class=\"wpb_text_column us_custom_6df4bc3a has_text_color\"><div class=\"wpb_wrapper\"><p>HYALOFAST\u00ae is a three-dimensional matrix made of pure hyaluronic acid for the treatment of chondral and osteochondral lesions. HYALOFAST\u00ae serves as a scaffold for the settlement of stem cells and cartilage cells and supports them in the regeneration of cartilage tissue.<\/p>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container us_custom_e032691c rightbox has_bg_color\"><div class=\"vc_column-inner\"><div class=\"w-html\"><div class=\"desk-spacer\" style=\"height:500px;\"><\/div>\n<div class=\"mobile-spacer\" style=\"height:0px;\"><\/div><\/div><div class=\"w-html\"><div style=\"clear:both;\"><\/div><\/div><div class=\"w-image us_custom_5051c2af mdr_logo align_right\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"563\" height=\"187\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2025\/09\/Logo-MDR-certified-0725.png\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2025\/09\/Logo-MDR-certified-0725.png 563w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2025\/09\/Logo-MDR-certified-0725-300x100.png 300w\" sizes=\"auto, (max-width: 563px) 100vw, 563px\" \/><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_3a0dc14f schmallercontentprodukte24 height_medium\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column produkt_intro_text\"><div class=\"wpb_wrapper\"><h2>ONE-STEP CARTILAGE REGENERATION<\/h2>\n<p>HYALOFAST\u00ae forms a scaffold for mesenchymal stem cells and is used for the treatment of cartilage injuries. These mesenchymal stem cells can be obtained and applied through bone marrow aspirate or concentrate, which is collected during surgery using Marrow Cellution\u2122. They can also migrate into the tissue after bone marrow stimulation or perforation. For the treatment of cartilage defects, bone marrow stimulation\u2014especially nanofracture using NanoFx\u00ae\u2014is a common technique to mobilize mesenchymal stem cells from the bone marrow.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_a4fbd29b breiterebloecke height_auto width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_grid cols_3 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:20px;\"><div class=\"wpb_column vc_column_container highlightboxprodukt hblue\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column produktehighlightbox\"><div class=\"wpb_wrapper\"><h4>Versatile in use<\/h4>\n<ul>\n<li>Indicated for chondral and osteochondral lesions<\/li>\n<li>Compatible with microfracture and stem cell procedures<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container highlightboxprodukt hgreen\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column produktehighlightbox\"><div class=\"wpb_wrapper\"><h4>Optimal handling<\/h4>\n<ul>\n<li>Easy application via arthroscopy or mini-arthrotomy<\/li>\n<li>Self-adherent and adaptable<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container highlightboxprodukt hgray\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column produktehighlightbox\"><div class=\"wpb_wrapper\"><h4>Safe<\/h4>\n<ul>\n<li>Fermentative production<\/li>\n<li>Based on 20 years of successful application of HYAFF\u00ae technology<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row schmallercontentprodukte24 height_medium\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"w-tabs layout_hor style_trendy switch_click\" style=\"--sections-title-size:1em\"><div class=\"w-tabs-list items_3 align_none\"><div class=\"w-tabs-list-h\"><button class=\"w-tabs-item active\" aria-controls=\"content-dea2\" aria-expanded=\"false\"><span class=\"w-tabs-item-title\">The dual role of Hyalofast\u00ae<\/span><\/button><button class=\"w-tabs-item\" aria-controls=\"content-uafd\" aria-expanded=\"false\"><span class=\"w-tabs-item-title\">Optimal handling<\/span><\/button><button class=\"w-tabs-item\" aria-controls=\"content-b2b4\" aria-expanded=\"false\"><span class=\"w-tabs-item-title\">Short and compact<\/span><\/button><\/div><\/div><div class=\"w-tabs-sections titles-align_none icon_chevron cpos_right\"><div class=\"w-tabs-section active\" id=\"dea2\"><button class=\"w-tabs-section-header active\" aria-controls=\"content-dea2\" aria-expanded=\"true\"><div class=\"w-tabs-section-title\">The dual role of Hyalofast\u00ae<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-dea2\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"g-cols wpb_row via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>For the treatment of chondral and osteochondral lesions<\/h3>\n<p>HYALOFAST\u00ae is a HYAFF\u00ae-based three-dimensional matrix made of pure hyaluronic acid for the treatment of chondral and osteochondral lesions of grade III\u2013IV (ICRS classification). The three-dimensional matrix supports stem cells and cartilage cells in their settlement and differentiation. HYALOFAST\u00ae thus stimulates natural regeneration and the formation of high-quality, hyaline-like cartilage in a short period of time.<\/p>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>Support for cartilage and bone damage<\/h3>\n<p>HYALOFAST\u00ae functions as a scaffold for mesenchymal stem cells and takes on a biological role. This core property is successfully used in the treatment of cartilage and bone damage by supporting chondrogenesis.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"1400\" height=\"616\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_image1_produktinfos_plasmaconcept_juni2019.jpg\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_image1_produktinfos_plasmaconcept_juni2019.jpg 1400w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_image1_produktinfos_plasmaconcept_juni2019-300x132.jpg 300w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_image1_produktinfos_plasmaconcept_juni2019-1024x451.jpg 1024w\" sizes=\"auto, (max-width: 1400px) 100vw, 1400px\" \/><\/div><\/div><div class=\"w-separator size_small with_line width_default thick_1 style_solid color_border align_center\"><div class=\"w-separator-h\"><\/div><\/div><div class=\"wpb_text_column us_custom_8d5aa4e2\"><div class=\"wpb_wrapper\"><h2>THE DUAL ROLE OF HYALOFAST\u00ae<\/h2>\n<\/div><\/div><div class=\"g-cols wpb_row via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>1. Structure and scaffold for cells<\/h3>\n<p><span class=\"deskonlypspacinghyalo\">As a three-dimensional tissue, HYALOFAST\u00ae promotes the settlement of mesenchymal stem cells while simultaneously contributing to defect filling. HYALOFAST\u00ae temporarily replaces the chondral and osteochondral tissue in the lesions until it is resorbed and replaced by new cartilage or bone tissue.<\/span><\/p>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>2. Biological support for cartilage regeneration<\/h3>\n<p>As a biopolymer made of pure hyaluronic acid, HYALOFAST\u00ae enables a controlled release of hyaluronic acid in situ. Mesenchymal stem cells (MSC) are attracted and their differentiation into cartilage or bone tissue is facilitated. Regenerative healing processes are initiated. This biological role makes HYALOFAST\u00ae unique worldwide.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"w-image us_custom_090aafef align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"1024\" height=\"359\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_image2_produktinfos_plasmaconcept_juni2019-1024x359-1.jpg\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_image2_produktinfos_plasmaconcept_juni2019-1024x359-1.jpg 1024w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_image2_produktinfos_plasmaconcept_juni2019-1024x359-1-300x105.jpg 300w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/div><\/div><div class=\"wpb_text_column bildunterschrift\"><div class=\"wpb_wrapper\"><p>Fig. 1: Treatment algorithm according to defect size and ICRS classification<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"uafd\"><button class=\"w-tabs-section-header\" aria-controls=\"content-uafd\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Optimal handling<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-uafd\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"g-cols wpb_row via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>One scaffold \u2013 many properties<\/h3>\n<p>HYALOFAST\u00ae is self-adherent and adaptable to the specific shape of the lesion. There is no need to distinguish between upper and lower sides. Fixation by suturing or gluing is usually not required. In addition, the properties of HYALOFAST\u00ae allow for easy arthroscopic implantation. The surgical effort differs little compared to microfracture.<\/p>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>One scaffold \u2013 many advantages<\/h3>\n<p>HYALOFAST\u00ae harnesses the body\u2019s self-healing potential and enables the regeneration of cartilage and bone tissue through a straightforward, minimally invasive surgical procedure. The body\u2019s own cartilage and stem cells independently migrate into the matrix within a short time, multiply, and rebuild the cartilage tissue. The use of HYALOFAST\u00ae is therefore extremely patient-friendly and also cost-efficient.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"b2b4\"><button class=\"w-tabs-section-header\" aria-controls=\"content-b2b4\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Short and compact<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-b2b4\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"g-cols wpb_row via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p><strong>Product:<\/strong> HYAFF\u00ae-based three-dimensional matrix<br \/>\n<strong>Content:<\/strong> 20 x 20 mm pad made of non-woven fibers<br \/>\n<strong>Approval:<\/strong> Medical device with CE marking and MDR approval<br \/>\n<strong>Sterilization:<\/strong> Gamma sterilized<br \/>\n<strong>Storage:<\/strong> Store dry (&lt; 40\u00b0 C)<\/p>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-separator size_medium with_line width_default thick_1 style_solid color_border align_center\"><div class=\"w-separator-h\"><\/div><\/div><div class=\"wpb_text_column us_custom_15f9d3f2\"><div class=\"wpb_wrapper\"><h2>More knowledge, more movement<\/h2>\n<\/div><\/div><div class=\"g-cols wpb_row via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h4>The evolution of hyaluronic acid<\/h4>\n<\/div><\/div><div class=\"wpb_text_column hyalotextspecial\"><div class=\"wpb_wrapper\"><p>Hyaluronic acid is considered a true all-rounder in medicine: whether as a lubricant and shock absorber in arthritic joints, as a filler for skin wrinkles, or as an artificial tear film in eye drops \u2014 hyaluronic acid is used in many ways as a highly viscous and pressure-resistant gel. Through HYAFF\u00ae technology (a patented esterification process), hyaluronic acid can be transformed into a biopolymer that modifies its chemical-physical properties while preserving its natural biological advantages.<\/p>\n<\/div><\/div><div class=\"wpb_text_column hyalotextspecial\"><div class=\"wpb_wrapper\"><p>The esterification process reduces the hydrophilicity of the molecule, making it possible to manufacture medical products that consist of pure hyaluronic acid while taking the form of solid fibers. The HYAFF\u00ae technology has been successfully used for 20 years in various medical fields. For the treatment of cartilage damage, HYAFF\u00ae technology offers an innovative solution in the form of HYALOFAST\u00ae.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"g-cols wpb_row us_custom_2ae65f69 via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"800\" height=\"533\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_hintergrundinfos_image1_plasmaconcept_juni2019.jpg\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_hintergrundinfos_image1_plasmaconcept_juni2019.jpg 800w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_hintergrundinfos_image1_plasmaconcept_juni2019-300x200.jpg 300w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"800\" height=\"533\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_hintergrundinfos_image2_plasmaconcept_juni2019.jpg\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_hintergrundinfos_image2_plasmaconcept_juni2019.jpg 800w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/HyaloFast_hintergrundinfos_image2_plasmaconcept_juni2019-300x200.jpg 300w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section>\n","protected":false},"excerpt":{"rendered":"The Matrix for Supporting Chondrogenesis HYALOFAST\u00ae is a three-dimensional matrix made of pure hyaluronic acid for the treatment of chondral and osteochondral lesions. HYALOFAST\u00ae serves as a scaffold for the settlement of stem cells and cartilage cells and supports them in the regeneration of cartilage tissue. ONE-STEP CARTILAGE REGENERATION HYALOFAST\u00ae forms a scaffold for mesenchymal...","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-4430","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Plasmaconcept - Hyalofast: One-Step Cartilage Regeneration<\/title>\n<meta name=\"description\" content=\"HYALOFAST\u00ae bildet ein Ger\u00fcst f\u00fcr mesenchymale Stammzellen und wird zur Behandlung von Knorpelsch\u00e4den eingesetzt.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Plasmaconcept - 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