{"id":4399,"date":"2022-07-04T12:14:32","date_gmt":"2022-07-04T10:14:32","guid":{"rendered":"https:\/\/dev.plasmaconcept.de\/cingal\/"},"modified":"2025-11-20T14:20:25","modified_gmt":"2025-11-20T13:20:25","slug":"cingal","status":"publish","type":"page","link":"https:\/\/dev.plasmaconcept.de\/en\/cingal\/","title":{"rendered":"Cingal"},"content":{"rendered":"<section class=\"l-section wpb_row us_custom_15767f81 slider_unterseite height_auto width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"g-cols wpb_row arteficalslider via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default reversed stacking_default\" style=\"--gap:0px;\"><div class=\"wpb_column vc_column_container us_custom_95304ca2 leftbox has_bg_color\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column us_custom_cd781b90 hide_mobile has_text_color\"><div class=\"wpb_wrapper\"><h1 class=\"slidertypo\">Immediate and long-lasting pain relief for osteoarthritis<\/h1>\n<\/div><\/div><div class=\"wpb_text_column us_custom_6df4bc3a has_text_color\"><div class=\"wpb_wrapper\"><p>CINGAL\u00ae is a highly effective preparation for the treatment of osteoarthritis. It combines the immediate anti-inflammatory and pain-relieving effect of the cortisone triamcinolone hexacetonide with the long-lasting effectiveness of cross-linked hyaluronic acid with a high active ingredient content for proven fast and long-lasting pain relief with just one injection.<\/p>\n<\/div><\/div><div class=\"w-image us_custom_b404458d align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"615\" height=\"310\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/cingal_produkt_slider_image_v1.png\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/cingal_produkt_slider_image_v1.png 615w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/cingal_produkt_slider_image_v1-300x151.png 300w\" sizes=\"auto, (max-width: 615px) 100vw, 615px\" \/><\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container us_custom_e032691c rightbox has_bg_color\"><div class=\"vc_column-inner\"><div class=\"w-html\"><div class=\"desk-spacer\" style=\"height:500px;\"><\/div>\n<div class=\"mobile-spacer\" style=\"height:0px;\"><\/div><\/div><div class=\"w-html\"><div style=\"clear:both;\"><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row schmallercontentprodukte24 height_medium\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column produkt_intro_text\"><div class=\"wpb_wrapper\"><h2>THE FIRST MONO-THERAPY WITH A COMBINATION OF HYALURONIC ACID AND CORTISONE<\/h2>\n<p>CINGAL\u00ae is the first ready-to-use combination product offering dual efficacy. When injected into the affected area, the crystal suspension slowly dissolves, providing immediate pain relief. The combination with cross-linked hyaluronic acid with a high active ingredient content results in long-lasting pain relief for at least 6 months.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row us_custom_a4fbd29b breiterebloecke height_auto width_full\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_grid cols_3 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:20px;\"><div class=\"wpb_column vc_column_container highlightboxprodukt cblue\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column produktehighlightbox\"><div class=\"wpb_wrapper\"><h4>2 in 1 \u2013 combination preparations<\/h4>\n<ul>\n<li>Unique combination of hyaluronic acid with patented crosslinking technology and the cortisone triamcinolone hexacetonide<\/li>\n<li>Fast and long-lasting pain relief<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container highlightboxprodukt corange\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column produktehighlightbox\"><div class=\"wpb_wrapper\"><h4>1+ Quality<\/h4>\n<ul>\n<li>Cross-linked hyaluronic acid with high active ingredient content (88 mg)<\/li>\n<li>Biotechnological fermentation manufacturing process, free from animal proteins<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container highlightboxprodukt cgray\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column produktehighlightbox\"><div class=\"wpb_wrapper\"><h4>A plus for patients<\/h4>\n<ul>\n<li>Only 1 injection per treatment cycle<\/li>\n<li>Fast and long-lasting pain relief and improved joint mobility<\/li>\n<li>For anyone who wants fast results and doesn&#8217;t have time for repeated injections<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/section><section class=\"l-section wpb_row schmallercontentprodukte24 height_medium\"><div class=\"l-section-h i-cf\"><div class=\"g-cols vc_row via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"w-tabs layout_hor style_trendy switch_click\" style=\"--sections-title-size:1em\"><div class=\"w-tabs-list items_3 align_none\"><div class=\"w-tabs-list-h\"><button class=\"w-tabs-item active\" aria-controls=\"content-ed75\" aria-expanded=\"false\"><span class=\"w-tabs-item-title\">Combined effect<\/span><\/button><button class=\"w-tabs-item\" aria-controls=\"content-k7f2\" aria-expanded=\"false\"><span class=\"w-tabs-item-title\">Long-lasting effectiveness<\/span><\/button><button class=\"w-tabs-item\" aria-controls=\"content-fab0\" aria-expanded=\"false\"><span class=\"w-tabs-item-title\">Short and compact<\/span><\/button><\/div><\/div><div class=\"w-tabs-sections titles-align_none icon_chevron cpos_right\"><div class=\"w-tabs-section active\" id=\"ed75\"><button class=\"w-tabs-section-header active\" aria-controls=\"content-ed75\" aria-expanded=\"true\"><div class=\"w-tabs-section-title\">Combined effect<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-ed75\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"g-cols wpb_row via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>CINGAL\u00ae is a highly effective preparation for the treatment of osteoarthritis. It combines the immediate anti-inflammatory and pain-relieving effect of the cortisone triamcinolone hexacetonide with the long-lasting effectiveness of cross-linked hyaluronic acid with a high active ingredient content for proven fast and long-lasting pain relief with just one injection.<\/p>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>The steroid triamcinolone hexacetonide has been used for decades as an intra-articular injection for persistent inflammation in the joint, such as arthritis or activated osteoarthritis. In the case of intra-articularly injected hyaluronic acid, the cross-linking of the molecules plays an important role. This slows down the enzymatic degradation of hyaluronic acid, thereby significantly prolonging its half-life in the joint.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"wpb_text_column us_custom_b072792d\"><div class=\"wpb_wrapper\"><p><span class=\"tag1\"> Day 1<\/span> <span class=\"monat1\">Month 1<\/span><\/p>\n<\/div><\/div><div class=\"w-image us_custom_623bf010 cingalimghighlight align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"1123\" height=\"328\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/cingal_content_kombinierte_wirkung_image1_v1.jpg\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/cingal_content_kombinierte_wirkung_image1_v1.jpg 1123w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/cingal_content_kombinierte_wirkung_image1_v1-300x88.jpg 300w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2024\/07\/cingal_content_kombinierte_wirkung_image1_v1-1024x299.jpg 1024w\" sizes=\"auto, (max-width: 1123px) 100vw, 1123px\" \/><\/div><\/div><div class=\"wpb_text_column us_custom_020a95dc\"><div class=\"wpb_wrapper\"><p><span class=\"wirkung1\">Immediate effect<\/span> <span class=\"wirkung2\">Long-lasting effect<\/span><\/p>\n<\/div><\/div><div class=\"wpb_text_column us_custom_8c42ed40\"><div class=\"wpb_wrapper\"><p class=\"bildunterschrift\">Fig. 1: Reduction in WOMAC pain score in % over the respective study period<\/p>\n<\/div><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Micronized particles of lipophilic cortisone are added as a particle suspension to the hydrophilic, viscoelastic hyaluronic acid gel. Neither the properties of hyaluronic acid nor those of cortisone are altered by combining them in the CINGAL\u00ae formulation.9 The combined mechanism of action of CINGAL\u00ae only takes effect when injected into the affected joint.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"k7f2\"><button class=\"w-tabs-section-header\" aria-controls=\"content-k7f2\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Long-lasting effectiveness<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-k7f2\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><h3>Fast and long-lasting effectiveness<\/h3>\n<\/div><\/div><div class=\"g-cols wpb_row via_grid cols_2-1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>CINGAL\u00ae is the first ready-to-use combination product offering dual efficacy. When injected into the affected area, the crystal suspension slowly dissolves, providing immediate pain relief. The combination with cross-linked hyaluronic acid with a high active ingredient content results in long-lasting pain relief for at least 6 months.<sup>8<\/sup><\/p>\n<ul>\n<li>\n<h4>CINGAL\u00ae provides faster pain relief than hyaluronic acid without cortisone<\/h4>\n<p>CINGAL\u00ae works faster than cross-linked hyaluronic acid alone. A significant reduction in pain is evident in weeks 1 and 3.<sup>10<\/sup><\/li>\n<\/ul>\n<ul>\n<li>\n<h4>Patients in the CINGAL\u00ae study confirm long-lasting pain relief<\/h4>\n<p>The course of pain reduction suggests that CINGAL\u00ae has a longer duration of action (significantly more than 26 weeks).<sup>10<\/sup><\/li>\n<\/ul>\n<p>CINGAL\u00ae is the first and only combination product that concentrates the treatment of activated osteoarthritis into a single injection.<\/p>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"w-image us_custom_a833bf3c image_border_content align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"413\" height=\"354\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/cingal-infografik2_image_plasmaconcept_250619.png\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/cingal-infografik2_image_plasmaconcept_250619.png 413w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/cingal-infografik2_image_plasmaconcept_250619-300x257.png 300w\" sizes=\"auto, (max-width: 413px) 100vw, 413px\" \/><\/div><\/div><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p class=\"bildunterschrift\">Fig. 2: Reduction in WOMAC pain score in % over the respective study period<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"fab0\"><button class=\"w-tabs-section-header\" aria-controls=\"content-fab0\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Short and compact<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-fab0\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"g-cols wpb_row us_custom_f79f129a via_grid cols_2 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default\" style=\"--gap:3rem;\"><div class=\"wpb_column vc_column_container us_custom_4de32527\"><div class=\"vc_column-inner\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><div style=\"display: flex;\">\n<div class=\"hide-mobile\"><\/div>\n<div><strong>Hyaluronic Acid Active Ingredient Content:<\/strong> 88 mg<br \/>\n<strong>Triamcinolone Hexacetonide Active Ingredient Content:<\/strong> 18 mg<br \/>\n<strong>Therapy:<\/strong> 1 injection<br \/>\n<strong>Contents:<\/strong> 1 prefilled syringe (4 ml)<br \/>\n<strong>Manufacturing:<\/strong> Fermentation<br \/>\n<strong>Production:<\/strong> Boston, USA<br \/>\n<strong>Indications:<\/strong> Approved for the knee joint<br \/>\n<strong>Approval:<\/strong> Medical device with CE marking<\/div>\n<\/div>\n<\/div><\/div><\/div><\/div><div class=\"wpb_column vc_column_container\"><div class=\"vc_column-inner\"><div class=\"w-image align_none\"><div class=\"w-image-h\"><img decoding=\"async\" width=\"561\" height=\"270\" src=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/cingal-verpackung_image_plasmaconcept_250619.png\" class=\"attachment-full size-full\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/cingal-verpackung_image_plasmaconcept_250619.png 561w, https:\/\/dev.plasmaconcept.de\/wp-content\/uploads\/2022\/07\/cingal-verpackung_image_plasmaconcept_250619-300x144.png 300w\" sizes=\"auto, (max-width: 561px) 100vw, 561px\" \/><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><div class=\"w-separator size_medium with_line width_default thick_1 style_solid color_border align_center\"><div class=\"w-separator-h\"><\/div><\/div><div class=\"wpb_text_column us_custom_15f9d3f2\"><div class=\"wpb_wrapper\"><h2>More knowledge, more movement<\/h2>\n<\/div><\/div><div class=\"w-tabs style_default switch_click accordion\" style=\"--sections-title-size:inherit\"><div class=\"w-tabs-sections titles-align_none icon_chevron cpos_right\"><div class=\"w-tabs-section\" id=\"b1af\"><button class=\"w-tabs-section-header\" aria-controls=\"content-b1af\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Arthosis is a widespread disease<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-b1af\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>Osteoarthritis is the most common joint disease worldwide and refers to the wear and tear of the joints. The mobility of the joint decreases and the affected patient loses the ability to move freely. The joint becomes inflamed, swells and hurts. The joints most commonly affected are the hand, knee, and hip joints, as they are subjected to the greatest strain in everyday movement. In principle, however, any other joint can also be affected. In Germany, an estimated 8 to 10 million people are affected. From an economic perspective, osteoarthritis is the most significant disease of the musculoskeletal system.<\/p>\n<p>While most people only experience occasional discomfort, around 2 million patients suffer from constant pain and severe mobility impairments. The number of people affected is set to rise in the coming years due to increasing life expectancy. But it is not only older people who are affected. Cartilage damage is becoming increasingly common in children and adolescents. In addition, there is a growing number of recreational athletes who participate in trendy and risky sports such as kitesurfing or downhill mountain biking. These sports put extreme strain on the joints, so that even younger people are increasingly experiencing arthritic symptoms.<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"w-tabs-section\" id=\"r62c\"><button class=\"w-tabs-section-header\" aria-controls=\"content-r62c\" aria-expanded=\"false\"><div class=\"w-tabs-section-title\">Cortisone and hyaluronic acid \u2013 a convincing team<\/div><div class=\"w-tabs-section-control\"><\/div><\/button><div  class=\"w-tabs-section-content\" id=\"content-r62c\"><div class=\"w-tabs-section-content-h i-cf\"><div class=\"wpb_text_column\"><div class=\"wpb_wrapper\"><p>As a group of active substances, cortisone performs numerous tasks in the metabolism and immune system. It slows down immune reactions and thus also acts against severe inflammation. Cortisone preparations suppress the misguided immune system and alleviate inflammation in the joints. In cases of inflammatory joint disease, they are injected directly into the joint in the form of crystal suspensions. Arthrosis patients with active arthrosis benefit from cortisone injections due to their anti-inflammatory effect and immediate pain relief, as the active ingredient quickly reaches the area where it is needed to combat the inflammation.<\/p>\n<p>Triamcinolone hexacetonide injections have been used for over 45 years due to their anti-inflammatory and pain-relieving properties. They take effect quickly, but their effect is typically short-lived.<\/p>\n<p>Triamcinolone has an anti-inflammatory effect that is five times stronger than the body&#8217;s own cortisol. The duration of action after injection into the joint is 3\u20134 weeks.<\/p>\n<p>Hyaluronic acid is a naturally occurring biocompatible molecule that is present in the human body. It plays a key role in tissue and especially in the joints. The maximum effect of hyaluronic acid after intra-articular injection occurs after 4-8 weeks. The properties of hyaluronic acid are crucial to its effectiveness. Cross-linked hyaluronic acids achieve significantly better results than low-molecular, simple hyaluronic acids. Hyaluronic acid with a slightly cross-linked molecular structure is optimally tolerated and the stabilized hyaluronans remain in the joint longer.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section>\n","protected":false},"excerpt":{"rendered":"Immediate and long-lasting pain relief for osteoarthritis CINGAL\u00ae is a highly effective preparation for the treatment of osteoarthritis. It combines the immediate anti-inflammatory and pain-relieving effect of the cortisone triamcinolone hexacetonide with the long-lasting effectiveness of cross-linked hyaluronic acid with a high active ingredient content for proven fast and long-lasting pain relief with just one...","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-4399","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Plasmaconcept - Cingal: Schmerzlinderung bei Arthrose<\/title>\n<meta name=\"description\" content=\"CINGAL\u00ae ist ein hochwirksames Pr\u00e4parat zur Behandlung der Arthrose. 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