Coagulation Division

The origin and one of the core focuses of Plasmaconcept is the professional care of hemophilia patients with the clotting factors essential to their survival. With more than ten years of experience in the distribution and handling of factor substitutes, the company is far more than just a supplier—Plasmaconcept is a specialist in this field. The company works closely with the most important treatment centers nationwide.

The origin and one of the core focuses of Plasmaconcept is the professional care of hemophilia patients with the clotting factors essential for their survival.

Plasmaconcept beliefert Praxen und Kliniken und entlastet die behandelnden Ärzte gleichzeitig von Aufgaben, die nicht notwendigerweise von ihnen erbracht werden müssen – Services, die den oft anstrengenden Alltag für Ärzte erleichtert und ihnen mehr Zeit für die Behandlung und Betreuung ihrer Patienten lassen.

In Germany, there are around 10,000 people who suffer from hemophilia, the so-called bleeding disorder. Even small injuries can be dangerous for these individuals because they lack the clotting factors that normally stop bleeding after a short time. Hemophilia is a genetic disorder and therefore hereditary. However, there are also spontaneous mutations that are considered the cause of hemophilia in about one third of affected individuals. According to current medical knowledge, hemophilia cannot be cured, but it can be treated.

Treatment is carried out with plasma-derived products, which can be obtained from plasma donations or produced through genetic engineering. Many different factors from blood plasma are involved in blood clotting. A healthy person produces these factors—mostly protein compounds—on their own. In people with hemophilia, protein synthesis is impaired. The majority of patients, around 80 percent, lack clotting factor VIII and therefore suffer from hemophilia A. Around 15 percent have hemophilia B, caused by a deficiency of clotting factor IX.

There are additional clotting disorders involving factors I through XVI, though these are less common. However, the consequences of all such factor deficiencies are the same for those affected: Not only external injuries, but especially internal bleeding—which occurs frequently and often goes unnoticed—can lead to serious complications. For many patients, the clotting disorder is so severe that they must regularly receive preventive injections of the clotting factor to avoid significant risks in their daily lives.

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